Conservation (genetics) Totally Explained

Everything about Conservation Genetics totally explained

Conservation refers to a high degree of similarity in orthologous DNA sequences, protein sequences, or protein structures amongst various phyla. A highly conserved protein is often related to an important cellular function. It had been widely believed that mutation in a highly conserved region leads to a non-viable life form, or a form that's eliminated through natural selection. Highly conserved proteins are often required for basic cellular function, stability or reproduction. Highly conserved DNA sequence is also thought to have functional value. The role for many of these highly conserved non-coding DNA sequences isn't understood. One recent study that eliminated four highly-conserved non-coding DNA sequences in mice yielded viable mice with no significant phenotypic differences; the authors described their findings as "unexpected".

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